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Central antiemetic actions of pimozide and haloperidol in the dog

โœ Scribed by H.K. Lee; C.Y. Chai; P.M. Chung; S.C. Wang


Book ID
118954067
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
714 KB
Volume
18
Category
Article
ISSN
0028-3908

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A positive and highly significant correlation was found between SC dose, plasma concentration, and antiemetic effect of haloperidol in the dog. To protect dogs from apomorphine-induced emesis, a concentration of 1 ng haloperidol/ml plasma was always sufficient, whereas protection from emesis was nev