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Central administration of small interfering RNAs in rats: A comparison with antisense oligonucleotides

✍ Scribed by Claudia Senn; Christoph Hangartner; Suzette Moes; Danilo Guerini; Karl G. Hofbauer

Book ID: 113585607
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 343 KB
Volume: 522
Category: Article
ISSN: 0014-2999
DOI: 10.1016/j.ejphar.2005.08.021

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## Abstract Activation of nuclear factor‐kappa B (NF‐κB) has been detected in various malignant tumors, including gastric carcinoma, and is associated with tumor growth, metastasis, resistance to chemotherapeutic agents and poor prognosis. Therefore, NF‐κB is a potential target for antitumor therap