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Central administration of insulin-like growth factor-I peptides inhibit depression-like inflammation-induced behavior of mice

✍ Scribed by R.H. McCusker; S. Park; R. Dantzer; K.W. Kelley


Book ID
116277300
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
36 KB
Volume
25
Category
Article
ISSN
0889-1591

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## Abstract High levels of insulin‐like growth factor‐1 (IGF‐1) have been associated with a significant increase in colon cancer risk. Additionally, IGF‐1 inhibits apoptosis and stimulates proliferation of colonic epithelial cells in vitro. Unfortunately, IGF‐1 knockout mice have severe development