𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Cellular Uptake, Distribution, and Degradation of Phosphorothioate Oligonucleotides in Euplotes crassus

✍ Scribed by L. L. THOMAS; C. M. PRICE


Book ID
119866979
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
258 KB
Volume
660
Category
Article
ISSN
0890-6564

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Maternal and fetal distribution of a pho
✍ Nicole V. Soucy; Jason P. Riley; Michael V. Templin; Richard Geary; Ann de Peyst πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 137 KB

## Abstract **BACKGROUND:** Fetal uptake of an antisense oligonucleotide was evaluated after intravenous (i.v.) dosing of ISIS 2105, a 20‐base phosphorothioate oligonucleotide, in timed‐pregnant Sprague‐Dawley rats. **METHODS:** To maximize the potential for fetal exposure, ISIS 2105 was administer