Cellular uptake of a novel cytotoxic age
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Ben D.-M. Chen; Alex Nakeff; Fred Valeriote
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Article
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1998
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John Wiley and Sons
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French
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Cryptophycin (CP) is a newly developed anticancer agent isolated from the terrestrial cyanobacteria of the genus Nostoc. CP is a mitotic inhibitor, causing cells to accumulate in mitosis with the disappearance of intracellular microtubules. In this report, we studied the interaction and uptake of a