## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
Cellular transformation, tyrosine kinase oncogenes, and the cellular adhesion plaque
β Scribed by Stuart Kellie
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 737 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0265-9247
No coin nor oath required. For personal study only.
β¦ Synopsis
Sum ma ry
The study of adhesion plaques in normal and transformed cells provides a series of phenotypic markers by which the process of transformation can be followed. Several proteins which are concentrated in adhesion plaques have now been identijied; a few of these can act as targets for tyrosine kinase. In an attempt to characterize the relationship between tyrosine phosphorylation and cell transformation, the reactions of three such proteins -vinculin, talin and integrinwith a range of tyrosine kinase oncogene products have been studied in detail.
π SIMILAR VOLUMES
## cellular activation Oxford Cell surface glycoproteins anchored to the plasma membrane via glycosylphosphatidylinositol (GPI) structures, and hence having no cytoplasmic domains, can nevertheless transmit activation signals in lymphocytes. By immunoprecipitation from detergent lysates and in vit