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Cellular senescence induced loss of stem cell proportion in the skin in vitro

✍ Scribed by Youn, Sang Woong; Kim, Dong Seok; Cho, Hyun Joo; Jeon, Sang Eun; Bae, In Hwa; Yoon, Ho Joon; Park, Kyoung Chan

Book ID
119292943
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
456 KB
Volume
35
Category
Article
ISSN
0923-1811

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## Abstract Vascular endothelial growth factor (VEGF) inhibitors, such as bevacizumab, have improved outcomes in metastatic colorectal cancer (CRC). Recent studies have suggested that VEGF can delay the onset of cellular senescence in human endothelial cells. As VEGF receptors are known to be upreg