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Cellular Senescence in Aging Primates

โœ Scribed by Herbig, Utz (author);Ferreira, Mark (author);Condel, Laura (author);Carey, Dee (author);Sedivy, John M. (author)


Book ID
111986301
Publisher
American Association for the Advancement of Science
Year
2006
Tongue
English
Weight
73 KB
Volume
311
Category
Article
ISSN
0036-8075

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Normal cells, with few exceptions, cannot proliferate indefinitely. Cell populations-in vivo and in culture-generally undergo only a limited number of doublings before proliferation invariably and irreversibly ceases. This process has been termed the finite lifespan phenotype or cellular senescence.