𝔖 Bobbio Scriptorium
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Cellular reactivity to respiratory syncytial virus in human colostrum and breast milk

✍ Scribed by Dr. R. Scott; M. Scott; G. L. Toms

Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
609 KB
Volume
17
Category
Article
ISSN
0146-6615

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✦ Synopsis

Colostrum and breast-milk samples were taken from 23 mothers between 2 days and 7 weeks postpartum and were examined for the presence of cellular reactivity to respiratory syncytial (RS) virus using a lymphocyte transformation assay. Positive responses were detected in nine of the 23 (39%) samples taken at 2-5 days postpartum, but this reactivity was undetectable at 3 weeks. Positive responses developed in a further three mothers during the 3-7-week period of lactation, suggesting a response to virus infection. Colostral whey was found to suppress the cellular response to RS virus and inhibition was related to the level of specific IgA antibody to RS virus present in the whey. The role of colostral cellular reactivity in protection of breast-fed infants from RS virus bronchiolitis is discussed.

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