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Cellular pharmacology of detorubicin and doxorubicin in L1210 cells

✍ Scribed by Zenebergh, A.; Baurain, R.; Trouet, A.


Book ID
123305373
Publisher
Elsevier Science
Year
1984
Weight
627 KB
Volume
20
Category
Article
ISSN
0277-5379

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We report on the individual and combined effects of doxorubicin (DOX) and hyperthermia (HYP) on nucleoid sedimentation and poly (ADP-ribose) polymerase (PARP) activity of L1210 cells. The effects of HYP and DOX on nucleoid sedimentation (increased sedimentation) were similar and correlated with cell