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Cellular mechanisms of ATP-induced hyperpolarization in renal epitheloid MDCK-cells

✍ Scribed by M. Paulmichl; J. Pfeilschifter; E. Wöll; F. Lang

Book ID
102885850
Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
820 KB
Volume
147
Category
Article
ISSN
0021-9541

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✍ F. Friedrich; H. Weiss; M. Paulmichl; E. Wöll; S. Waldegger; F. Lang 📂 Article 📅 1991 🏛 Springer 🌐 English ⚖ 1001 KB

ATP activates K+ channels by increasing intracellular calcium activity in Madin Darby canine kidney (MDCK) cells. The present study has been performed to test for the involvement of G-proteins and of protein kinase C in the intracellular transmission of these effects. To this end, the effect of ATP