## Abstract Cultured skin fibroblasts from a patient with Tโcell immune deficiency and an absence of purine nucleoside phosphorylase activity in red cells were assayed for their capacity to metabolize inosine and guanosine. The cultured fibroblasts were lacking activity of nucleoside phosphorylase
โฆ LIBER โฆ
Cellular immunodeficiency associated with nucleoside phosphorylase deficiency: Immunologic and biochemical studies
โ Scribed by Robert Sandman; Arthur J. Ammann; Charles Grose; Diane W. Wara
- Book ID
- 118373375
- Publisher
- Elsevier Science
- Year
- 1977
- Tongue
- English
- Weight
- 437 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1090-2341
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Cultured skin fibroblasts from a 2-year-old boy with an atypical form of beta-galactosidase deficiency have been studied. With the artificial substrate 4-methylumbelliferyl-beta-D-galactopyranoside, 5--15% residual activity was found in fibroblasts from this patient. Most of this activity was in the