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Cellular heterogeneity of CFTR expression and function in the lung: implications for gene therapy of cystic fibrosis

✍ Scribed by Jiang, Qinshi; Engelhardt, John F


Book ID
110024673
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
1023 KB
Volume
6
Category
Article
ISSN
1018-4813

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Cystic fibrosis is a common, fatal disorder caused by abnormalities in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. CFTR encodes a chloride channel that regulates secretion in many exocrine tissues. The presentation of cystic fibrosis is highly variable as measured by the age