𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Cellular Effects of Small Molecule PTP1B Inhibitors on Insulin Signaling †

✍ Scribed by Xie, Laiping; Lee, Seung-Yub; Andersen, Jannik N.; Waters, Steve; Shen, Kui; Guo, Xiao-Ling; Moller, Niels Peter H.; Olefsky, Jerrold M.; Lawrence, David S.; Zhang, Zhong-Yin


Book ID
126856662
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
412 KB
Volume
42
Category
Article
ISSN
0006-2960

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Toward the discovery of small molecule P
✍ Andrew J. Nichols; Robert D. Mashal; Bork Balkan 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 203 KB 👁 2 views

## Abstract PTP1B is a protein tyrosine phosphatase involved in insulin and leptin signaling and is a primary mechanism for down‐regulating both the insulin and leptin receptor signaling pathways. Animals deficient in PTP1B have improved glucose regulation and lipid profiles and are resistant to we

Effects of small molecule inhibitors of
✍ Lova Segerström; Ninib Baryawno; Baldur Sveinbjörnsson; Malin Wickström; Lotta E 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 French ⚖ 691 KB

## Abstract Activation of the PI3K/Akt signaling pathway is correlated with poor prognosis in neuroblastoma, the most common and deadly extracranial tumor of childhood. In this study, we show that the small‐molecule inhibitors of phosphoinositide‐dependent protein kinase‐1 (PDK1) OSU03012 and the d