Paracetamol pharmacokinetics during the
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L. Beaulac-Baillargeon; S. Rocheleau
📂
Article
📅
1994
🏛
Springer
🌐
English
⚖ 362 KB
Paracetamol pharmacokinetics was evaluated in groups of pregnant (8-12 weeks) and non pregnant women given the standard oral dose of 650 mg. The mean half-life was significantly lower and oral clearance was significantly higher in the first trimester group compared to the control group. The AUC was