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Cellular delivery and biological activity of metall complex-peptide conjugates

✍ Scribed by Katrin Splith; Jan Hoyer; Ines Neundorf

Book ID
113569218
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
77 KB
Volume
15
Category
Article
ISSN
1359-6446

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Cellular uptake and biological activity
Cellular uptake and biological activity of peptide nucleic acids conjugated with peptides with and without cell-penetrating ability
✍ Yvonne Turner; Gerd Wallukat; Pille SÀÀlik; Burkhard Wiesner; Stephan Pritz; Joh πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 383 KB

## Abstract A 12‐mer peptide nucleic acid (PNA) directed against the nociceptin/orphanin FQ receptor mRNA was disulfide bridged with various peptides without and with cell‐penetrating features. The cellular uptake and the antisense activity of these conjugates were assessed in parallel. Quantitatio