Randomization of Amyloid-β-Peptide(1-42)
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Ana M. Saraiva; Isabel Cardoso; Maria João Saraiva; Klaus Tauer; M. Carmo Pereir
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Article
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2010
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John Wiley and Sons
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English
⚖ 541 KB
## Abstract The amyloid‐β peptide (Aβ) plays a central role in the mechanism of Alzheimer's disease, being the main constituent of the plaque deposits found in AD brains. Aβ amyloid formation and deposition are due to a conformational switching to a β‐enriched secondary structure. Our strategy to i