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Cellular and molecular mechanisms responsible for progression of Barrett's metaplasia to esophageal carcinoma

โœ Scribed by Beilstein, Michelle; Silberg, Debra


Book ID
123163718
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
167 KB
Volume
17
Category
Article
ISSN
0889-8588

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## BACKGROUND. The rate of incidence of esophageal adenocarcinoma has surpassed that of all other malignancies in the U.S. Esophageal adenocarcinoma arises from Barrett's esophagus through the multistep accumulation of genetic mutations in metaplastic cells, accompanied by histologic changes from