Cellular Adhesion Regulates bFGF Gene Expression in Human Retinal Pigment Epithelial Cells
β Scribed by Laurie M. Bost; Amy E. Aotaki-Keen; Leonard M. Hjelmeland
- Book ID
- 115604796
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 991 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0014-4835
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## Abstract We investigated the expression profile of monocyte chemoattractant proteinβ1 (MCPβ1) in human retinal pigment epithelial (RPE) cells under different culture conditions and evaluated the molecular mechanism responsible for __MCPβ1__ gene expression in RPE cells. After cellular confluence
The human retinal pigment epithelium (RPE) is a potential target tissue for directed transfer of candidate genes to treat age-related macular degeneration (AMD). The RPE is uniquely suited to gene therapy protocols that use liposome-mediated DNA transfer because of its high intrinsic phagocytic func