xxi, 318 p. : 24 cm
Cellular Adhesion: Molecular Definition to Therapeutic Potential
β Scribed by David A. Cheresh (auth.), Brian W. Metcalf, Barbara J. Dalton, George Poste, Judy Schatz (eds.)
- Publisher
- Springer US
- Year
- 1994
- Tongue
- English
- Leaves
- 332
- Series
- New Horizons in Therapeutics
- Edition
- 1
- Category
- Library
No coin nor oath required. For personal study only.
β¦ Synopsis
The books in this acclaimed series provide integrated, critical surveys of topics of current interest to the pharmaceutical industry. Cellular Adhesion: Molecular Definition to Therapeutic Potential covers the molecular definition of adhesion molecule structure and function, the biological consequences of cellular adhesion, and the therapeutic potential of targeting adhesion molecules.
β¦ Table of Contents
Front Matter....Pages i-xxi
Front Matter....Pages 1-1
The Biological Function of Ξ²3 Integrins and Other Vitronectin Receptors....Pages 3-24
Integrin Modulating Factor and the Regulation of Leukocyte Integrins....Pages 25-35
StructureβFunction Aspects of SelectinβCarbohydrate Interactions....Pages 37-53
Recognition of Cell Surface Carbohydrates by C-Type Animal Lectins....Pages 55-75
The UvomorulinβCatenin Complex....Pages 77-92
Cytotactin....Pages 93-106
Adhesion Molecules and Bone Remodeling....Pages 107-132
Front Matter....Pages 133-133
Effects of Shear Stress on Leukocyte Adhesion....Pages 135-151
Blockade of Leukocyte Adhesion in in Vivo Models of Inflammation ....Pages 153-166
Proadhesive Cytokine Immobilized on Endothelial Proteoglycan....Pages 167-172
Lung Inflammation and Adhesion Molecules....Pages 173-186
Adhesion Molecule-Dependent Cardiovascular Injury....Pages 187-212
GPIIb/IIIa Antagonists as Novel Antithrombotic Drugs....Pages 213-237
Front Matter....Pages 239-239
The Pathological Consequences of Bacterial Adhesion to Medical Devices....Pages 241-257
Peptide Mimetics as Adhesion Molecule Antagonists....Pages 259-290
Derivation of Therapeutically Active Humanized and Veneered Anti-CD18 Antibodies....Pages 291-312
Back Matter....Pages 313-318
β¦ Subjects
Pharmacology/Toxicology; Animal Anatomy / Morphology / Histology; Plant Sciences
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