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Cell volume regulation in mouse TA3 ascites tumor cells by exogenous ATP as measured by the coulter counter

✍ Scribed by G. Gasic; C. Stewart


Publisher
John Wiley and Sons
Year
1968
Tongue
English
Weight
195 KB
Volume
71
Category
Article
ISSN
0021-9541

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✦ Synopsis


Exogenous ATP can induce a marked cell enlargement in TA3 tumor cells which can 'be reversed or prevented by Ca and Mg. This regulatory effect on cell volume is specific for ATP. The mechanism probably involves changes in cell ionic content. Received Nov. 14. '67. Acceuted Mav 15. '68. 1 Supported by USPHS grantCA 08476 USPHS grant 5 TO 1 CA 05022 and by ant DRE 949 bf the Damon Runyon Memorial Fund %r Cancer Research Inc. 2 9 gm NaCI, 40 ml 0.154 M KCL, 85~m1'0.110 M NazHP04, 15 ml 0.110 M NaHzPOa, and distilled water up to a hter.