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Cell Type-Specific Targeting with Surface-Engineered Lentiviral Vectors Co-displaying OKT3 Antibody and Fusogenic Molecule

✍ Scribed by Haiguang Yang; Kye-Il Joo; Leslie Ziegler; Pin Wang

Book ID
106493735
Publisher
Springer US
Year
2009
Tongue
English
Weight
772 KB
Volume
26
Category
Article
ISSN
0724-8741

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## Abstract The development of a lentiviral system to deliver genes to specific cell types could improve the safety and the efficacy of gene delivery. Previously, we have developed an efficient method to target lentivectors to specific cells via an antibody–antigen interaction in vitro and in vivo.