## Abstract Naphthalene is metabolized in the lung and liver to reactive intermediates by cytochrome P450 enzymes. These reactive species deplete glutathione, covalently bind to proteins, and cause necrosis in Clara cells of the lung. The importance of glutathione loss in naphthalene toxicity was i
Cell toxicity of methacrylate monomers-The role of glutathione adduct formation
β Scribed by Ansteinsson, V.; Kopperud, H. B.; Morisbak, E.; Samuelsen, J. T.
- Book ID
- 120754858
- Publisher
- John Wiley and Sons
- Year
- 2013
- Tongue
- English
- Weight
- 386 KB
- Volume
- 101
- Category
- Article
- ISSN
- 1549-3296
No coin nor oath required. For personal study only.
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## Abstract Methacrylate monomers that are found to leach from cured resinβbased dental materials induce biological effects __in vitro__. The underlying mechanisms have not been fully elucidated although involvement of increased cellular reactive oxygen species (ROS) and DNAβdamage has been suggest