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Cell systems and the toxic mechanism(s) of α-synuclein

✍ Scribed by Mark R. Cookson; Marcel van der Brug

Book ID
116459163
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
175 KB
Volume
209
Category
Article
ISSN
0014-4886

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## Abstract Parkinson's disease (PD) is generally sporadic but a number of genetic diseases have parkinsonism as a clinical feature. Two dominant genes, α‐synuclein (__SNCA__) and leucine‐rich repeat kinase 2 (__LRRK2__), are important for understanding inherited and sporadic PD. __SNCA__ is a majo