Cell Surface Receptors: A Short Course on Theory and Methods

✍ Scribed by Lee E. Limbird (auth.)

• Publisher: Springer US
• Year: 1996
• Tongue: English
• Leaves: 250
• Edition: 2
• Category: Library

✦ Synopsis

Cell Surface Receptors: A Short Course on Theory and Methods, SecondEdition is a primer for the study of cell surface receptors. The simplified discussion of methods and their underlying principles removes the usual intimidation caused by the specialized vocabulary or sophisticated mathematics that characterize many of the primary papers in this field. In this way, the basic concepts become emphasized. This volume is a starting point: a textbook as well as a manual to which the investigator can return for a refresher course, when needed.

✦ Table of Contents

Front Matter....Pages i-xvii
Historical Perspective....Pages 1-26
Methods for Characterization of Receptors Based on Receptor-Mediated Responses in Tissue or Intact Cell Preparations....Pages 27-60
Identification of Receptors Using Direct Radioligand Binding Techniques....Pages 61-122
Complex Binding Phenomena....Pages 123-167
The Preparation and Study of Detergent-Solubilized Receptors....Pages 169-199
The Topographical Fate of Ligand-Receptor Complexes as Reflected by the Properties of Ligand Binding to Intact Cells....Pages 201-232
Back Matter....Pages 233-238

✦ Subjects

Pharmacology/Toxicology; Laboratory Medicine