Cell surface binding simian virus 40 large t antigen becomes anchored and stably linked to lipid of the target cells

Response of normal and oncogene-transfor

Response of normal and oncogene-transformed human mammary epithelial cells to transforming growth factor β1 (TGF-β1): Lack of growth-inhibitory effect on cells expressing the simian virus 40 large-t antigen

✍ Fulvio Basolo; Lisa Fiore; Fortunato Ciardiello; Simonetta Calvo; Gabriella Font 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 French ⚖ 825 KB

The relationship between the expression of selected oncogenes having different modes of action and the loss of the capacity t o respond in vitro to transforming growth factor+ I (TGF-P I) was analyzed in human mammary epithelial cells (MEC). Primary MEC cultures from healthy donors and the spontaneo