Leptin signaling in breast cancer: An ov
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Donatella Cirillo; Anna Maria Rachiglio; Raffaele la Montagna; Antonio Giordano;
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Article
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2008
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John Wiley and Sons
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English
β 141 KB
π 1 views
## Abstract The adipocyteβderived peptide leptin acts through binding to specific membrane receptors, of which six isoforms (obRaβf) have been identified up to now. Binding of leptin to its receptor induces activation of different signaling pathways, including the JAK/STAT, MAPK, IRS1, and SOCS3 si