Cell selectivity, mechanism of action and LPS-neutralizing activity of bovine myeloid antimicrobial peptide-18 (BMAP-18) and its analogs

Antimicrobial activity, bactericidal mec

Antimicrobial activity, bactericidal mechanism and LPS-neutralizing activity of the cell-penetrating peptide pVEC and its analogs

✍ Yong Hai Nan; Il-Seon Park; Kyung-Soo Hahm; Song Yub Shin 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 891 KB

__p__VEC is a cell‐penetrating peptide derived from the murine vascular endothelial‐cadherin protein. To evaluate the potential of __p__VEC as antimicrobial peptide (AMP), we synthesized __p__VEC and its analogs with Trp and Arg/Lys substitution, and their antimicrobial and lipopolysaccharide (LPS)‐