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Cell Segregation and Lysis Have Profound Effects on the Growth of Escherichia coli in High Cell Density Fed Batch Cultures

✍ Scribed by Lena Andersson; Lars Strandberg; Sven-Olof Enfors

Book ID: 109387820
Publisher: American Institute of Chemical Engineers
Year: 1996
Tongue: English
Weight: 125 KB
Volume: 12
Category: Article
ISSN: 8756-7938
DOI: 10.1021/bp950069o

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## Abstract Overflow metabolism is an undesirable characteristic of aerobic cultures of __Escherichia coli__. It results from elevated glucose consumption rates that cause a high substrate conversion to acetate, severely affecting cell physiology and bioprocess performance. Such phenomenon typicall