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Cell proliferation, cell death and angiogenesis in early and advanced gastric cancer of intestinal type

✍ Scribed by Carla Vindigni; Clelia Miracco; Donatella Spina; Loretta Presenti; Marcella Gallorini; Rosella Vatti; Alfonso De Stefano; Franco Roviello; Enrico Pinto; Maria I. Filipe; Piero Tosi

Publisher
John Wiley and Sons
Year
1997
Tongue
French
Weight
119 KB
Volume
74
Category
Article
ISSN
0020-7136

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✦ Synopsis

Mitotic (MI) and apoptotic index (AI), the sum of the 2, i.e., the turnover index (TI), tumor neovascularization (NV) and p53 expression, as well as tumor grading and node status, are evaluated in early and advanced gastric-cancer cases. T1 cases show significantly less frequent lymph-node invasion and lower tumor grade, and, taken together, have significantly lower MI, Al and TI and higher values of NV than the T2-3 cases. However, correlation of the variables shows that the above-mentioned discrimination is due to a minority of T1 cases (11 out of 33), while the majority of them are allocated in the same 95% ellipse of tolerance of the T2-3 cases.

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