𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Cell proliferation and chromosomal damage in human leukocytes: dicentries and premature chromosome condensations in first, second, and third mitoses after X-irradiation

✍ Scribed by Bernd Beek


Publisher
Springer
Year
1981
Tongue
English
Weight
265 KB
Volume
57
Category
Article
ISSN
0340-6717

No coin nor oath required. For personal study only.

✦ Synopsis


The frequencies of dicentric chromosomes and of partial premature chromosome condensation (PCC) in definitely first, second, or third mitoses after X-irradiation of human leukocytes, as determined with a bromodeoxyuridine (BUdR)/ Giemsa labeling technique, were investigated. The results show that practically no PCCs occur in first mitoses after irradiation and culture start in contrast to second or third ones. The frequencies of dicentrics from first to second, as well as from second to third mitoses after irradiation decline by about 50% for each division step.