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Cell-pool tryptophan phases in ergot alkaloid fermentation

✍ Scribed by Z. Řeháček; K. A. Malik

Book ID
112923211
Publisher
Springer Netherlands
Year
1971
Tongue
English
Weight
293 KB
Volume
16
Category
Article
ISSN
0015-5632

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Four tryptophan dependent mutants of Claviceps purpurea 1029 N5 were derived by treatment with N-methyl-N′-nitro-N-nitroguanidine (NTG) and protoplasting of the treated fungus. The poor alkaloid production of these mutants required a systematic optimisation of the production media. Malic acid was es