CELL-MEDIATED IMMUNITY TO HERPES VIRUS TYPE-1 IN PATIENTS WITH RECURRENT CORNEAL HERPES SIMPLEX
β Scribed by HELGA HAMMER; ATTILA DOBOZY
- Book ID
- 114921056
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2009
- Tongue
- English
- Weight
- 232 KB
- Volume
- 58
- Category
- Article
- ISSN
- 1755-375X
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## Abstract To evaluate whether herpes simplex virus type 1 (HSVβ1) replicates in freshly isolated human mononuclear cells (HMNC) and results in cellmediated immunity, HMNC purified from the peripheral blood of a healthy HSVβ1βseronegative individual were infected with HSVβ1 (KOS strain). The kinet
Lewis rats were infected by corneal scarification with HSV type 1 type strain F virus. The animals showed symptoms of infection and inflammatory infiltrates of the eye but little mortality. After one month, immune responses to viral and autoantigens were examined. It was shown that lymph node cells