Cell-mediated immune responses to α-fetoprotein and other antigens in hepatocellular carcinoma
✍ Scribed by Shahriar Behboudi; Sandra Boswell; Roger Williams
- Book ID
- 111239249
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 137 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0106-9543
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📜 SIMILAR VOLUMES
Hepatocellular carcinoma (HCC) is the fifth most common malignancy worldwide, with a poor prognosis and limited therapeutic options. Therefore, the development of novel therapeutic strategies is of high priority. ␣-Fetoprotein (AFP) is overexpressed in the majority of HCCs. Priming of immune respons
## Abstract α‐Fetoprotein (AFP) is a commonly used tumor marker in the detection of hepatocellular carcinoma (HCC), and its sensitivity and specificity is insufficient to detect HCC in all patient samples. Recently, the immunocomplexed forms of AFP (AFP‐IgM) have been reported to be present in HCC
## Abstract Hepatocellular carcinoma (HCC) is one of the most common malignancies with a poor prognosis and limited therapeutic options that is often characterized by the expression of the tumor‐associated antigen α‐fetoprotein (AFP). CD4+ helper T cells are important in generating potent anticance