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Cell-mediated DNA inhibition and 6-TG mutagenicity of V79 cells with chemical carcinogens

✍ Scribed by D. Slamenová; A. Gabelová

Book ID
113250132
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
138 KB
Volume
85
Category
Article
ISSN
0165-1161

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## Abstract Chemically non‐reactive carcinogens, such as polycyclic hydrocarbons, have to be metabolized by cellular enzymes in order to exert their biological effects including mutagenicity. Chinese hamster V79 cells can be efficiently mutated from 8‐azaguanine susceptibility to resistance by N‐me