Cell-derived proteases and protease inhibitors as regulators of neurite outgrowth
โ Scribed by Denis Monard
- Book ID
- 118390685
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 483 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0166-2236
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๐ SIMILAR VOLUMES
This review summarizes studies on the reciprocal regulation of neuroblastoma neurite outgrowth by thrombin and protease nexin-1 (PN-1). PN-1 recently was shown to possess the same deduced amino acid sequence as the glial-derived neurite-promoting factor. The neurite outgrowth activity of PN-1 depend
Astroglial-conditioned medium (GCM) induced two distinct, but intimately related, phases of neuritogenesis in NB2ddl neuroblastoma cells-a "rapid-outgrowth," unstable phase, and a delayed, relatively stable phase, which are apparently regulated by glialderived protease inhibitors and laminin, respec
Protease nexin-1 (PN-1) is a protein proteinase inhibitor recently shown to be identical with the glial-derived neurite-promoting factor or glial-derived nexin. It has been shown to promote neurite outgrowth in neuroblastoma cells and in sympathetic neurons. The present experiments were designed to