𝔖 Bobbio Scriptorium
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Cell density affects the binding of the toxic lectin abrin to HeLa cells in monolayer cultures

✍ Scribed by Kirsten Sandvig

Book ID
115908403
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
185 KB
Volume
89
Category
Article
ISSN
0014-5793

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✍ Olsnes, Sjur ;Sandvig, Kirsten ;Eiklid, Kristin ;Pihl, Alexander πŸ“‚ Article πŸ“… 1978 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 604 KB

The toxic lectin modeccin, which inhibits protein synthesis in eukaryotic cells, is cleaved upon treatment with 2-mercaptoethanol into two peptide chains which move in polyacrylamide gels at rates corresponding to molecular weights 28,000 and 38,000. After reduction, the toxin loses its effect on ce