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Cell death after dorsal root injury

✍ Scribed by Daniel J. Chew; Veronica H.L. Leinster; Mathuri Sakthithasan; Lesley G. Robson; Thomas Carlstedt; Peter J. Shortland

Book ID
116770133
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
244 KB
Volume
433
Category
Article
ISSN
0304-3940

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## Abstract A significant loss of neurons in the dorsal root ganglia (DRG) has been reported in animal models of peripheral nerve injury. Neonatal sensory neurons are more susceptible than adult neurons to axotomy‐ or nerve growth factor (NGF) withdrawal‐induced cell death. To develop therapies for