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Cell death: a trigger of autoimmunity?

✍ Scribed by R.J.T. Rodenburg; J.M.H. Raats; G.J.M. Pruijn; W.J. van Venrooij

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
174 KB
Volume
22
Category
Article
ISSN
0265-9247

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## Abstract Suicidal erythrocyte death or eryptosis is characterized by cell shrinkage and cell membrane scrambling with phosphatidylserine (PS) exposure at the erythrocyte surface. Triggers of eryptosis include increase in cytosolic Ca^2+^ activity, formation of ceramide and energy depletion. Exce