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Cell cycle variations in chromatin structure detected by DNase I

โœ Scribed by D.A. Prentice; R.A. Tobey; L.R. Gurley


Book ID
115891931
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
720 KB
Volume
157
Category
Article
ISSN
0014-4827

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We have recently described a novel nuclear antigen, AF-2, which is related to cell cycle dependent alterations of chromatin structure. We show by two parameter flow cytometry on a cell by cell basis that the antigen is accessible to specific monoclonal antibodies only in mitotic and postmitotic earl