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Cell cycle target validation: approaches and successes

✍ Scribed by Peter M. Fischer; Graham Bell; Carol Midgley; Roger Sleigh; David M. Glover


Book ID
114410321
Publisher
Elsevier Science
Year
2003
Weight
242 KB
Volume
2
Category
Article
ISSN
1477-3627

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In this review, we will focus on the role played by transcription factors of the E2F/DP family in controlling the expression of genes that carry out important cell-cycle control functions, thereby ensuring ordered progression through the mammalian cell division cycle. The emerging picture is that ce