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CELL CYCLE RESPONSES TO DNA DAMAGE IN P53 WT CANCER CELL LINES

✍ Scribed by OLIVIER, Magali; THEILLET, Charles

Book ID
123209918
Publisher
Portland Press
Year
1996
Tongue
English
Weight
184 KB
Volume
88
Category
Article
ISSN
0248-4900

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✍ Magali Olivier; Silvia Bautista; HΓ©lΓ¨ne VallΓ¨s; Charles Theillet πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 257 KB πŸ‘ 1 views

The role of the p53 protein in mediating G 1 and G 2 cell-cycle arrests after genotoxic insult has been clearly and reproducibly established in primary diploid fibroblasts, but data obtained from p53 wild-type (wt) cancer cell lines are inconsistent. Furthermore, a large proportion of human tumors h