Cell cycle-related changes in regulatory volume decrease and volume-sensitive chloride conductance in mouse fibroblasts
β Scribed by P. Doroshenko; V. Sabanov; N. Doroshenko
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 189 KB
- Volume
- 187
- Category
- Article
- ISSN
- 0021-9541
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π SIMILAR VOLUMES
## Abstract Our aim was to test the effect of hypotonicity and extracellular Ca^2+^ (Ca~o~) on cell volume and membrane potential (V~M~) in barnacle muscle cells. Under isotonic conditions the resting V~M~ of isolated cells mounted in the experimental chamber exposed to either Ca^2+^βfree or Ca^2+^
During exposure to a hypotonic solution (55% osmolarity), cultured human epithelial (Intestine 407) cells exhibit a regulatory volume decrease after osmotic swelling. This process is known to involve parallel activation of volume-regulatory K + and C1-conductances. Biphasic increase in the cytosolic