Cell-cycle regulatory sequences in a hamster histone promoter and their interactions with cellular factors

Epidermal growth factor initiates DNA sy

Epidermal growth factor initiates DNA synthesis after a time-dependent sequence of regulatory events in Swiss 3T3 cells—interactions with hormones and growth factors

✍ Angela M. Otto; Marie-Odile Ulrich; Luis Jimenez de Asua 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 English ⚖ 701 KB

Epidermal growth factor (EGF) stimulates the initiation of DNA synthesis in Swiss 3T3 cells after a constant prereplicative period of 14-15 hours. The final rate of initiation follows apparent first-order kinetics and can thus be quantified by a rate constant k. The value of k can be changed by late