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Cell Cycle Regulated Transport Controlled by Alterations in the Nuclear Pore Complex

✍ Scribed by Taras Makhnevych; C.Patrick Lusk; Andrea M. Anderson; John D. Aitchison; Richard W. Wozniak


Book ID
117269741
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
480 KB
Volume
115
Category
Article
ISSN
0092-8674

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We have recently described a novel nuclear antigen, AF-2, which is related to cell cycle dependent alterations of chromatin structure. We show by two parameter flow cytometry on a cell by cell basis that the antigen is accessible to specific monoclonal antibodies only in mitotic and postmitotic earl