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Cell cycle molecules define a pathway required for neuron death in development and disease

✍ Scribed by Lloyd A. Greene; David X. Liu; Carol M. Troy; Subhas C. Biswas


Book ID
116270554
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
328 KB
Volume
1772
Category
Article
ISSN
0925-4439

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## Abstract __unpaired__ (__upd__) encodes a ligand for the Jak/STAT signaling pathway in __Drosophila__. In the second instar and early third larval eye disc, __upd__ is expressed in the center of the posterior margin. __upd__ loss‐of‐function mutations caused eye size reduction and __upd__ overex