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Cell-cycle deregulation in progressive CML

โœ Scribed by Savona, Michael; Talpaz, Moshe


Book ID
109948080
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
116 KB
Volume
8
Category
Article
ISSN
1474-1776

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## Abstract Brk is a cytoplasmic nonreceptor tyrosine kinase that is overexpressed in breast tumors but undetectable in normal or benign mammary tissues. Brk promotes proliferation of human mammary epithelial cells and tumor growth in a mouse model, but the role of Brk in cell cycle regulation is n