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Cell cycle dependent expression and stability of the nuclear protein detected by Ki-67 antibody in HL-60 cells

✍ Scribed by S. Bruno; Z. Darzynkiewicz


Book ID
114715932
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
627 KB
Volume
25
Category
Article
ISSN
0960-7722

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We have recently described a novel nuclear antigen, AF-2, which is related to cell cycle dependent alterations of chromatin structure. We show by two parameter flow cytometry on a cell by cell basis that the antigen is accessible to specific monoclonal antibodies only in mitotic and postmitotic earl