𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Cell Cycle Checkpoints as Therapeutic Targets

✍ Scribed by Zoe A. Stewart; Jennifer A. Pietenpol


Book ID
110376089
Publisher
Springer US
Year
1999
Tongue
English
Weight
386 KB
Volume
4
Category
Article
ISSN
1083-3021

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Cell cycle checkpoints and their impact
✍ Alan Eastman πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 168 KB

## Abstract Cells contain numerous pathways designed to protect them from the genomic instability or toxicity that can result when their DNA is damaged. The p53 tumor suppressor is particularly important for regulating passage through G~1~ phase of the cell cycle, while other checkpoint regulators

Cell-cycle checkpoints and cancer
✍ Kastan, Michael B.; Bartek, Jiri πŸ“‚ Article πŸ“… 2004 πŸ› Nature Publishing Group 🌐 English βš– 702 KB
E2F target genes and cell-cycle checkpoi
✍ Patrizia Lavia; Pidder Jansen-DΓΌrr πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 97 KB πŸ‘ 1 views

In this review, we will focus on the role played by transcription factors of the E2F/DP family in controlling the expression of genes that carry out important cell-cycle control functions, thereby ensuring ordered progression through the mammalian cell division cycle. The emerging picture is that ce