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Cell culture-based models for intestinal permeability: A critique

โœ Scribed by Praveen V. Balimane; Saeho Chong

Book ID
114384975
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
224 KB
Volume
10
Category
Article
ISSN
1359-6446

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Models predictive of intestinal drug absorption are important in drug development to identify compounds with promising biopharmaceutical properties. Since permeability is a factor affecting absorption, cell culture models (e.g., Caco-2, MDCK) have been developed to predict drug transport from the in